Keanu

Jordan Peele

Rell Williams / Oil Dresden

Keegan-Michael Key

Clarence Goobril / Smoke Dresden

Keanu Reeves

Keanu (voice)

Tiffany Haddish

Hi-C

Method Man

Cheddar

Darrell Britt-Gibson

Trunk

Jason Mitchell

Bud

Jamar Malachi Neighbors

Stitches

Luis Guzmán

Bacon

Will Forte

Hulka

Nia Long

Hannah

Rob Huebel

Spencer

Madison Wolfe

Alexis

Jordyn A. Davis

Belle

James Yeargain

Donnie

Brittany Seymour

Rachel

Richard Holden

Detective Mank

Nadiyah Skyy Taylor

Galaxy

Susan McBrien

Hulka's Mom

Jenny Ballard

Officer Jonah